DragonSlayer,

After reading hundreds of stories and listening to top researchers about gut health and Autoimmune Diseases, I think that SIBO has a much larger role in AS and autoimmune disease for the majority of people.

Could the original Ebringer theory be partially incorrect? I guess if one really had a large overgrowth of klebsiella in the large intestine that could trigger an immune response. I read that the klebs live in everyone's large intestine in a healthy and small amount. I also heard that starch barely reaches the large intestine during digestion, and is primarily absorbed at some point in the small intestine. Meaning that starch as food source, are going to feed the klebs in the small intestine a hell of a lot more.

People like Dr. William Davis speak about SIBO leading to leaky gut and autoimmune diseases. Could the spread of Klebsiella and other fecal bacteria from the large intestine, into the small intestine be the main driver of AS in the majority of the population who suffer from it?

Rather than the original theory about AS being triggered from klebsiella in the large intestine. I'm talking about the majority of AS cases...


I think for people like my father who wasn't really affected by AS until later in age, this might be the case. He only had slight pain on occasion and would take long to heal once injured, and lived a normal life until old age. Now as he got much older, his AS kicked in badly after using NSAID (which affects small intestine) for an injury and getting the COVID shot (which disrupts gut balance in small intestine).


Since klebsiella is supposed to be a fecal bacteria and part of a healthy balance in the large intestine, maybe the Immune response to klebs in the large intestine isn't much at all, if any...

Let me know what you think...

I'm also seeing how a restrictive diet is counterproductive for the growth of good bacteria in the small intestine, which is needed to produce a defense against Fecal bacteria in the small intestine. From my understanding, if there isn't enough good bacteria in the small intestine, then it will be easy for Fecal bacteria from the large intestine to spread and cause SIBO...

Best Regards

Jonathan