I'm taking several pulsed low dose antibiotics as part of the Marshall Protocol. It includes Minocycline, Azithromycin and Bactrim. I've been on the protocol for about 3 years now and am doing excellent. I haven't taken any pain relievers for a couple of years now other than for an occasional headache etc. I'm back to being able to work full time and play hard including dirt bike riding and skateboarding. Note that the antibiotics are only part of the protocol so I can't tell you how much effect they would have alone...